A very interesting article was listed in news-medical.net this week. The open access article called ‘Animal-sourced foods improve child nutrition in Africa’ by Khonje and Qaim used representative data from five African countries—Ethiopia, Malawi, Nigeria, Tanzania, and Uganda—to show that the consumption of animal-sourced foods (ASF) contributes to improving child nutritional outcomes and that these […]
Author: ulick
Nigeria and DR Congo
Two articles in Malaria World pertaining to the two countries with the largest numbers of deaths attributed to malaria caught my attention. The first is the lead article, a BBC report about vaccine rollout in Nigeria the most afflicted country with 26.8% of deaths. The article describes the roll-out of the new vaccine called R21/Matrix-M […]
Attractive Targeted Sugar Bait Stations Do Not Prevent Malaria
A very interesting article in Malaria Journal by Ashton et al, Efficacy of attractive targeted sugar bait stations (ATBS) against malaria in Western Province Zambia: epidemiological findings from a two-arm cluster randomized phase III trial, describes a large real world trial of the efficacy of sugar baits affixed to the walls of buildings laced with […]
AIDS in Africa
This week I introduce similarities and differences of the approach to AIDS and Malaria in Africa. African friends express more concern about AIDS and HIV. In many cases that have known victims and it seems a more real threat. I have not examined HIV/AIDS in any great detail as many others more qualified on the […]
New Drug in Development – PfCLK3 Inhibitor
Malaria World this week featured the news – New drug could help fight against treatment-resistant malaria. The article referenced by Scottish researchers Brettell et al was published in the Journal of Medicinal Chemistry and is entitled Targeting Pf CLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment. In summary, the novel compounds developed inhibit […]
Caution Recommended using Indoor Residual Spraying during Pregnancy
For the second time in recent weeks, I am glad to report that some malaria researchers are questioning the use of insecticides to combat malaria. A proof copy of a review paper by Oberlin et al entitled ‘Effect of Indoor Residual Spraying on Malaria in Pregnancy and Pregnancy Outcomes: A Systematic Review’ was included in […]
What Next? Intramuscular Injections of Atovaquone Derivative
This week in Malaria World, MMV (Medicines for Malaria Venture), a Swiss based NGO founded with funding from Rockefeller foundation and others, announced clinical trials of MMV371, an ester-linked acetyl derivative of atovaquone, one of the components of GSKs Malarone, a combination of atovaquone and proguanil that is taken orally. Drugs.com report side effects for […]
Some Malaria Researchers are Concerned They are Poisoning the Planet
I was pleasantly surprised to note that the lead article in malaria world this week is an article by the editor of Malaria World Journal, Bart Knols, expressing concern about the impact of chemicals used for mosquito control. In the article entitled ‘A shot in the foot: Could chemical control of malaria vectors threaten food […]
Mosquito Transmission of Malaria – Deeply Engrained Belief
Three articles this week reminded me how unquestioned the belief that malaria is spread by insect vectors is. This belief is supported by confirmation bias. Every result that suggests a connection is highlighted. Any evidence that does not support the belief is explained away or ignored. This is no different than the approach of Ross […]
Primaquine to children – Cure for malaria or a poison?
In Malaria World this week there is reference to a study purported to support an increase in the dosage of Primaquine to children with Plasmodium vivax malaria. However, is that the main conclusion that can be taken from the study? The study, ‘Primaquine for uncomplicated Plasmodium vivax malaria in children younger than 15 years: a […]